Electrochemotherapy (ECT) is a breakthrough localized cancer treatment that significantly enhances drug uptake in tumor cells through short, high-voltage electrical pulses. This clinically proven method improves the effectiveness of chemotherapy agents, leading to higher tumor response rates with minimal side effects.
Fast and minimally invasive:
• The procedure takes only 20–30 minutes and is performed with local anesthesia or mild sedation, ensuring patient comfort.
Versatile combination therapy:
• Electrochemotherapy can be effectively combined with chemotherapy, radiotherapy, surgery, and immunotherapy (IL-12) for enhanced tumor control and better treatment outcomes.
Safe and well-tolerated:
• Adheres to international clinical guidelines, ensuring high patient safety with mild and minimal side effects compared to conventional cancer treatments.
Accelerated healing and recovery:
• Patients experience reduced pain, bleeding, secretions, and inflammation within 48 hours, leading to improved local control of tumoral lesions and the quality of life.
Effective tumor regression:
• Noticeable tumor shrinkage typically occurs within 2 to 4 weeks, offering a rapid and measurable response to treatment.
High response rates across multiple cancer types:
• Electrochemotherapy is effective for a wide range of primary and metastatic tumors, including cutaneous, subcutaneous, and even deep-seated malignancies, offering a promising alternative to conventional therapies.
At OnMed, we are committed to delivering the latest advancements in electroporation therapies to improve treatment outcomes with precision, safety, and efficiency.
Where and When to Use SENNEX® Electrochemotherapy?
SENNEX® Electrochemotherapy (ECT) is an innovative, minimally invasive local treatment aimed at controlling cutaneous and subcutaneous metastases from various types of cancers. By combining electric pulses with established chemotherapy agents, SENNEX® dramatically enhances the absorption of the drug directly into tumor cells, leading to more effective tumor destruction.
This targeted approach not only improves local tumor control but also offers significant benefits in terms of pain relief, wound healing, and quality of life for patients with advanced or recurrent disease. SENNEX® can be applied regardless of the primary tumor origin, making it an essential palliative option for patients who are not suitable candidates for surgery, radiotherapy, or systemic treatments.
SENNEX® Device: Certified, Portable, and Designed for Clinical Efficiency
The SENNEX® Electrochemotherapy (ECT) system is a CE-certified medical device, designed for safe and reliable performance in clinical settings. Its compact and portable design allows for easy transport and rapid setup—enabling healthcare professionals to perform treatments efficiently, even in outpatient or bedside environments.
With an intuitive touchscreen interface and pre-set protocols, SENNEX® streamlines the treatment process, minimizing preparation time and ensuring precision at every step. This makes it an ideal solution for busy oncology teams seeking to provide effective, patient-centered care with ease and confidence.
Device and
Certification
The SENNEX® system with Electroporation (ECT) device is designed for greater ease of operation. The device is portable and can be assembled in a few minutes.
Advanced Tumour Therapy
Chemotherapy enhanced with the aid of electric pulses. It is applied directly at the site of the tumor.
Working Principle
A very low dose of a chemotherapy drug and an electrical pulse (electroporation) can be used for effective and safe treatment of a spectrum of sicknesses.
SENNEX® Electroporation device - the new way to "zap" and "destroy" tumors (explainer video of SENNEX®)
SENNEX®
Precision Electrochemotherapy for Localized Cancer Treatment
SENNEX® is an advanced Electroporation Therapy (EPT) platform. The Electrochemotherapy (ECT) system is designed for a precise local tumor targeting. By means of electrical pulses, it enhances chemotherapy drug uptake directly into the cancer cells and optimizes tumor control for well-defined lesions.
With specialized SENNEX® needle electrodes, the system precisely delivers electric pulses to the tumor site, enhancing chemotherapy absorption through electroporation for more effective treatment in a reversible electric field.
The treatment is tailored to tumor size and location, applied either non-invasively through the skin or directly to exposed tumor tissue during surgery. SENNEX® electrochemotherapy is a minimally invasive approach that maximizes drug absorption, improving treatment efficacy while preserving healthy tissue.
Key benefits of SENNEX™ Electrochemotherapy
- Clinically proven effectiveness: SENNEX™ has demonstrated high response rates in patients with difficult-to-treat cancers, including skin, head & neck, and recurrent tumors resistant to conventional therapies. Clinical studies show tumor control and complete response in many patients where other treatments have failed.
- Minimal side effects: Since SENNEX™ works locally and enhances the effect of low-dose chemotherapy only at the tumor site, the surrounding healthy tissues are preserved, reducing the risk of harsh systemic side effects.
- Single or limited sessions needed: SENNEX™ treatments are often completed in a single or few short sessions, under local anesthesia, offering a patient-friendly alternative to prolonged chemotherapy or radiation courses.
- Potential immune-boosting effect: By triggering immunogenic cell death, SENNEX™ may stimulate the immune system, offering synergy when combined with systemic immunotherapies.
- Option for patients with limited alternatives: SENNEX™ opens a treatment window for patients with radio-resistant, recurrent, or inoperable tumors, helping those who have exhausted conventional options or for whom surgery is not viable.
News and Updates
20 July, 2020
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Great idea to keep improving
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20 July, 2020
Reading Time: 3min
Great idea to keep improving
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book…
20 July, 2020
Reading Time: 3min
Great idea to keep improving
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry’s standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book…