Electroporation + Chemotherapy
1. A chemotherapeutic drug is first injected either intravenously or locally in the tumor area.
2. The SENNEX® ElectroChemoTherapy (ECT) system delivers short high voltage electric pulses that make the cell membrane highly permeable to the drug.
3. When the electric pulses are stopped, the cell membrane reseals and regains its low permeability. The drug gets trapped inside the cells.
4. The DNA is destroyed, resulting in mitotic cell death that spares non-dividing cells (muscle and nerve). ECT also significantly reduces the blood supply to the tumor cells.