SENNEX^® ElectroChemoTherapy (ECT) is chemotherapy done with the aid of electric pulses. It is applied directly at the site of the tumor. Short electric pulses make the cell membranes transiently permeable. As a result, the intracellular accumulation of the chemotherapeutic drug can be increased substantially. ECT is used for local treatment and control of tumors. Effects on bleeding and secretion are often seen in a few days.

Bleomycin and Cisplatin are the two drugs currently used for ECT. Bleomycin can be administered intra-tumorally or intravenously, depending on the number and size of the tumors. Cisplatin can be administered only intra-tumorally.

SENNEX^® ECT is a quick procedure which can be done under local or general anesthesia. It usually takes about 20 to 30 minutes. When done under local anesthesia, the patient can be sent home after an observation period of a few hours. Patients may experience minor pain after the procedure. This pain can usually be managed with routine painkillers. Antibiotics are usually not required, but can be recommended for some patients.

SENNEX^® ECT can be used independently of previous treatments like chemotherapy, radiotherapy and/or surgery. The effects are usually seen within 2 days to 4 weeks. The treatment can be repeated multiple times if necessary.